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Techno-Economic Analysis (TEA) for Biotech, Food-Tech & Sustainable Processes
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Why Techno-Economic Analyses Still Surprise Me — Even After 20+ Years in Scale-Up
Even after 20+ years in process development and industrial scale-up, techno-economic analyses continue to reveal unexpected constraints. This article explores the real-world surprises TEAs uncover — and why seeing them early can change how startups design, scale, and invest.
Gustavo Valente
5 days ago4 min read


Inside a Techno-economic Analysis: What Biotech Founders Get Wrong About Costs, Yields & Scale-Up — and How to Fix It
Most founders enter the Techno-Economic Analysis (TEA) process thinking it’s “just a model that will tell me how much my product will cost.” In reality, TEA often becomes the first time a team sees their entire bioprocess and scale-up pathway without the comfort of early-stage assumptions. And when that happens, three things emerge: hidden cost drivers unrealistic expectations scale-up realities that no one teaches in the lab or academia These aren’t criticisms. They are pa
Gustavo Valente
Dec 3, 20254 min read


Scaling Where It Makes Sense: How Techno-Economic Analysis (TEA) Guides Plant Location, Scale, and Timing
Every founder scaling a biotech or foodtech process knows the feeling, lying awake at 2 a.m., running scenarios in their head: Where should we build? When will be the right time? And how big before it’s too big? Techno-Economic Analysis (TEA) gives you a framework to answer all three, with data, not gut feeling or personal preferences. It translates technical progress into business logic, helping founders make decisions that investors trust. 1️⃣ WHERE — Site & Region Selecti
Gustavo Valente
Oct 21, 20255 min read


𝗦𝗰𝗮𝗹𝗶𝗻𝗴 𝗨𝗽 𝘄𝗶𝘁𝗵 𝗧𝗘𝗔 𝗦𝘂𝗽𝗽𝗼𝗿𝘁: 𝗧𝘂𝗿𝗻𝗶𝗻𝗴 𝗟𝗮𝗯 𝗣𝗿𝗼𝗴𝗿𝗲𝘀𝘀 𝗶𝗻𝘁𝗼 𝗠𝗮𝗿𝗸𝗲𝘁 𝗥𝗲𝗮𝗱𝗶𝗻𝗲𝘀𝘀
Scaling up a bioprocess from the laboratory to a pilot plant or from pilot to demo is one of the most exciting and risky stages for any startup. The leap from proof-of-concept to pilot or industrial production brings not only technical challenges but also financial uncertainty. That’s where Techno-Economic Analysis (TEA) comes in. At Sustech Innovation , we help biotech, foodtech, and sustainable-materials companies translate their technical data into clear economic insigh
Gustavo Valente
Oct 14, 20254 min read


Techno-Economic Analysis (TEA) for Biotech & Food-Tech: Beyond Basic Feasibility
When scaling up a biotech or food-tech process, the big question isn’t just “is it feasible?” . It’s “will this process make sense...
Gustavo Valente
Sep 29, 20254 min read


Understanding the Importance of TEA in Early-Stage Biotech
(Hint: It’s not just about cost per kg, it’s about stepping back from R&D and seeing the full picture) I’ve heard this many times: “We...
Gustavo Valente
Sep 19, 20252 min read


“𝐖𝐡𝐲 𝐞𝐯𝐞𝐫𝐲 𝐟𝐨𝐮𝐧𝐝𝐞𝐫 𝐧𝐞𝐞𝐝𝐬 𝐚 𝐓𝐞𝐜𝐡𝐧𝐨-𝐄𝐜𝐨𝐧𝐨𝐦𝐢𝐜 𝐀𝐧𝐚𝐥𝐲𝐬𝐢𝐬 (𝐓𝐄𝐀) 𝐨𝐟 𝐭𝐡𝐞𝐢𝐫 𝐨𝐰𝐧 𝐟𝐚𝐜𝐭𝐨𝐫𝐲, 𝐞𝐯𝐞𝐧 𝐢𝐟 𝐭𝐡𝐞𝐲’𝐥𝐥 𝐧𝐞𝐯𝐞𝐫 𝐛𝐮𝐢𝐥𝐝 𝐢𝐭.”
I hear this a lot from founders: 👉 “Our plan is to use CMOs.” 👉 “We’ll license the tech anyway, so why bother with a facility TEA?”...
Gustavo Valente
Aug 21, 20252 min read


"𝐖𝐞’𝐫𝐞 𝐧𝐨𝐭 𝐫𝐞𝐚𝐝𝐲 𝐟𝐨𝐫 𝐚 𝐓𝐄𝐀 𝐲𝐞𝐭, 𝐰𝐞’𝐫𝐞 𝐬𝐭𝐢𝐥𝐥 𝐯𝐚𝐥𝐢𝐝𝐚𝐭𝐢𝐧𝐠 𝐚𝐧𝐝 𝐨𝐩𝐭𝐢𝐦𝐢𝐬𝐢𝐧𝐠 𝐭𝐡𝐞 𝐩𝐫𝐨𝐜𝐞𝐬𝐬."
I hear this often. And every time, my brain freezes for a second. 🤯 Why? Because 𝐭𝐡𝐚𝐭’𝐬 𝐚𝐜𝐭𝐮𝐚𝐥𝐥𝐲 𝐭𝐡𝐞 𝐩𝐞𝐫𝐟𝐞𝐜𝐭...
Gustavo Valente
Aug 13, 20251 min read


🔍 𝐖𝐡𝐞𝐧 𝐁𝐢𝐠𝐠𝐞𝐫 𝐈𝐬𝐧’𝐭 𝐁𝐞𝐭𝐭𝐞𝐫: 𝐇𝐨𝐰 𝐎𝐯𝐞𝐫𝐞𝐬𝐭𝐢𝐦𝐚𝐭𝐢𝐧𝐠 𝐒𝐜𝐚𝐥𝐞 𝐇𝐮𝐫𝐭𝐬 𝐘𝐨𝐮𝐫 𝐅𝐮𝐧𝐝𝐫𝐚𝐢𝐬𝐞 𝐏𝐢𝐭𝐜𝐡
Everyone talks about the “Valleys of Death” in biotech — but here’s one few mention: 🚨 Building your business case around the wrong...
Gustavo Valente
Jul 22, 20251 min read
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